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- W2372034678 abstract "Objective To study the clinical pathological characteristics of fatal infectious mononucleosis(FIM)and its differential diagnosis. Methods An autopsy case of FIM was studied by histopathological observation and immunohistochemical staining. Results A large number of proliferative atypical lymphocytes were observed in tissues of the lymph nodes, the tonsil, the spleen and other lymphoid tissues. Their primitive normal structure appeared was distorder or lost completely, even necrosis in the tonsil. In addition, the atypical lymph cells showed infiltration in tissues of the other organs and systems, especially around the small blood vessels. Immunohistochemically, EBV was positive in a few cells. Proliferalive atypical lymphocytes were positive for CD20 and negtive for CD3. Conclusion FIM is an autoimmune disease that is infected by EBV and its death is rare. The fatal causes of patients with FIM may be correlated with immunity dysfunction and genetic factor." @default.
- W2372034678 created "2016-06-24" @default.
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- W2372034678 date "2004-01-01" @default.
- W2372034678 modified "2023-09-26" @default.
- W2372034678 title "Fatal infectious mononucleosis:an autopsy case report and review of literature" @default.
- W2372034678 hasPublicationYear "2004" @default.
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