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- W2372052163 abstract "OBJECTIVE To investigate the effect of budesonide inhalation on Mycoplasma pneumoniae(MP) infection-induced asthma in children and its impact on the levels of inflammatory factors in vivo,so as to provide basis for the clinical treatment.METHODS A total of 228 cases of asthma chindren with confirmed MP infection but not with gasping symptoms were collected as the research subjects and randomly divided into budesonide inhalation treatment group(observation group)(113cases)and conventional treatment group(control group)(115 cases).The effects of the two therapeutic methods on lung function,clinical symptoms and inflammatory factor levels were analyzed.RESULTS Forced expiratory volume(FEV1.0)(91.42± 6.50),peak expiratory flow(PEF)(96.80±14.32),the first second forced expiratory volume and forced vital capacity ratio(FEV1.0/FVC)(82.40±5.21)of observation group were significantly higher than those of control group((68.98 ±6.41),(71.25±12.58),(72.35±5.42)respectively),and the differences were significant(P0.05).The improving of clinical symptoms including difficulty in breathing,coughing,pulmonary rale of observation group was significantly better than that of the control group(P 0.05).The levels of inflammatory factors including tumor necrosis factor(TNF-A),interleukin 6,8(IL-6,IL-8)of observation group((221.4±33.5)ng/L,(145.5 ±31.2)ng/L,(78.5±19.6)ng/L respectively)were significantly lower than those of control group(385.5 ±31.2)ng/L,(217.4±38.5)ng/L(105.4±22.8)ng/L respectively)(P0.05).CONCLUSIONBudesonide inhalation can effectively improve lung function and clinical symptoms,and reduce the levels of inflammatory factors.It plays a great role in the prevention of MP infection-induced acute attack of asthma." @default.
- W2372052163 created "2016-06-24" @default.
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- W2372052163 date "2014-01-01" @default.
- W2372052163 modified "2023-09-26" @default.
- W2372052163 title "Efficacy of budesonide inhalation on prevention of Mycoplasmapneumoniae infection-induced acute attack of asthma" @default.
- W2372052163 hasPublicationYear "2014" @default.
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