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- W2372102253 abstract "[Objective]To observe the effect of desmopressin acetate(DDAVP)on patients’ BP,HR,volume of blood loss,time-consuming of surgery and velocity of blood loss in patients underwent FESS.[Methods]100 ASA Ⅰ-Ⅱ patients were randomly allocated to DDAVP group(D group)and controlled group(C group),and there were 50 patients in each group. DDAVP 0.15 μg/kg was given by vein infusion 10 min before induction,following DDAVP 0.15 μg/kg/h given by pump infusion in D group. The total DDAVP dose was no more than 0.3μg/kg. The same volume of normal saline was given by the same way in C group. Observed patients’ MAP and HR at the time of arriving operative room,end of induction,end of tracheal intubation,beginning of operation,10 min and 30 min after operation,end of operation and tracheal extubation. Measured patients’ volume of blood loss by weighing method. Recorded operation duration time and calculated velocity of blood loss in 2 groups.[Results]The MAP of D group patients was significantly lower than that of C group patients at the time of end of induction,end of endotracheal intubation,beginning of operation,10 min and 30 min after operation,end of operation. The HR of D group patients was significantly faster than that of C group patients at time of end of induction. The volume of blood loss and the velocity of blood loss of D group patients were less than those of C group patients. The time-consuming of D group patients was significantly less than that of C group patients.[Conclusion]DDAVP could lower blood pressure,reduce the volume of blood loss and slow down the velocity of blood loss of FESS patients during operation,which facilitate the operation and shorten operative time. It is a safe and efficient method." @default.
- W2372102253 created "2016-06-24" @default.
- W2372102253 creator A5039039777 @default.
- W2372102253 date "2011-01-01" @default.
- W2372102253 modified "2023-09-23" @default.
- W2372102253 title "THE EFFECT OF DESMOPRESSIN ACETATE ON FESS" @default.
- W2372102253 hasPublicationYear "2011" @default.
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