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- W2372137813 abstract "Objective Explore the cerebral protective effect of Batroxobin and Butylphthalide on acute cerebral infarction and its possible mechanism;Investigate the effect of the Batroxobin United Butylphthalide on the treatment of acute cerebral infarction.Methods The sutural method is used for the production of the middle cerebral artery infarction.Observation on rat focal cerebral ischemia injury in rats before and after the hs-CRP's and D-dimer's level changes of cerebral infarction area and observe the effects of combined application of batroxobin and butylphthalide on acute cerebral ischemia damage.Results ①On 24h after cerebral ischemia in rats were measured the results showed that the area of cerebral infarction:The treatment group and the comparison of cerebral ischemia group,there were significant difference(P0.05);The combined grop with a single drug groups have obvious difference(P0.05);②D-dimer in cerebral ischemia group was significantly higher than that in normal group(P0.05);The treatment group and the comparison of cerebral ischemia group,there were significantdifferences.(P0.05);The combined grop with a single drug grop have obvious difference.(P0.05);③ hs-CRP in cerebral ischemia group was significantly higher than that in normal group(P0.05);The treatment group and the comparison of cerebral ischemia group,there were significantdifferences.(P0.05);The combined grop with a single drug grop have obvious difference.(P0.05).Conclusion By reducing the D-dimer and ultra-sensitivity C-reactive protein levels,Tobishi batroxobin and butylphthalide can reduce the infarct size of acute cerebral infarction.Tobishi batroxobin and butylphthalide have a cerebral protective effect, and combination therapy better." @default.
- W2372137813 created "2016-06-24" @default.
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- W2372137813 date "2013-01-01" @default.
- W2372137813 modified "2023-09-26" @default.
- W2372137813 title "The effect of Batroxobin and Butylphthalide on the Cerebral Ischemia Injury in Rats" @default.
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