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- W2372155652 abstract "Objective:To analyze the relationship between the genotype and phenotype of autosomal dominant polycystic kidney disease(ADPKD) in Han nationality in East China. Methods: Seventy nine ADPKD patients were studied by the method of polymerase chain reaction(PCR) single strand complement polymorphism(SSCP).The clinical data of the ADPKD2 patients and ADPKD1 patients were collected.The relationship between the genotype and phenotype, including the onset age and major symptoms such as liver cyst, hypertension, urinary infection, urinary lithiasis, hematuria was analyzed statistically. Results: The average onset age of ADPKD2 was 9.7 years later than that of ADPKD1 [(46.09±9.86) years vs (36.38±11.35) years]( P 0.05),but the major symptoms had no significant difference between the 2 groups. Conclusion: The symptoms of ADPKD2 are similar with that of ADPKD1,but the average onset age is later than the latter." @default.
- W2372155652 created "2016-06-24" @default.
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- W2372155652 date "2003-01-01" @default.
- W2372155652 modified "2023-09-25" @default.
- W2372155652 title "Relationship between genotype and phenotype of autosomal dominant polycystic kidney disease" @default.
- W2372155652 hasPublicationYear "2003" @default.
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