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- W2372156749 abstract "Objective To investigate the effect of the RGD-containing cellular adhesion tripeptides on human stomach cancer BGC823,and to study the function of the RGD tripeptide in inducing BGC823 apoptosis.Methods BGC823 cells were treated with the RGD tripeptides at various concentrations.MTT assay was used to examine the growth and proliferation of BGC823 cells after treatment with the RGD tripeptides for 48 hours.HE staining and electromicroscope were used to observe the morphology of apoptotic cells,and Survivin,flow cytometry were also used to analyze the BGC823 apoptosis.Results the RGD tripeptides significantly inhibits the growth and proliferation of BGC823 cells in dose-dependent manner.Conclusion the RGD-containing cellular adhesion tripeptide may inhibit tumour cell growth and proliferation through inducing apoptosis.Induce apoptosis caused by mitochondria.In these processes,RGD is of high conservation." @default.
- W2372156749 created "2016-06-24" @default.
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- W2372156749 date "2011-01-01" @default.
- W2372156749 modified "2023-09-23" @default.
- W2372156749 title "Prelimenary studies on effects of the RGD-containing cellular adhesion tripeptides on inhibiting growth of BGC823 and inducing its apoptosis" @default.
- W2372156749 hasPublicationYear "2011" @default.
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