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- W2372173852 abstract "Objective To investigate the target organ lesion and its mechanism in rat model of qideficiency and blood-stasis syndrome from the aspect of glucose and lipid metabolism and oxidative stress reaction of heart and brain tissue.Method The rat model of qi-deficiency and blood-stasis syndrome was established by using exhaustive swimming.After 1,2 or 4 weeks the levels of blood glucose,blood lipid, serum lipoprotein,and the contents of malondialdehyde(MDA)and superoxide dismutase(SOD)of heart and brain tissue were detected respectively.Result In the model group the level of blood glucose increased after 1,2 or 4 weeks.The levels of plasma total cholesterol(TC)and triglyceride(TG) decreased,and high-density lipoprotein-C(HDL-C)and low-density lipoprotein-C(LDL-C)had no changes after 4 weeks.The content of heart MDA increased,and the contents of heart SOD,brain MDA and SOD had no significant changes in rats of model group.Conclusion The disorder of glucose and lipid metabolism is an important biological basis of qi-deficiency and blood-stasis syndrome.The target organ lesion may be related closely to oxidative stress reaction." @default.
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- W2372173852 date "2009-01-01" @default.
- W2372173852 modified "2023-09-25" @default.
- W2372173852 title "Glucose and lipid metabolism and oxidative stress reaction in rat model of qi-deficiency and blood-stasis syndrome" @default.
- W2372173852 hasPublicationYear "2009" @default.
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