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- W2372200229 abstract "Recent researches have found that the exposure of the developing mammalians during the period of synaptogenesis to drugs that transiently block N-methyl-D-asparate glutamate receptors or that transiently potentiate gamma-amino butyric acid receptors can trigger widespread apoptotic neurodegeneration in the brains,even in the spinal cords.These drugs include general anesthetics,anticonvulsants,alcohol,etc.The brain growth spurt period,also called synaptogenesis occurs in humans from the third trimester of pregnancy to three years after birth.The time windows include late pregnancy,neonate period and infancy.Therefore,people pay much more attention to the question how these drugs impact the development of the human central nervous system.Elucidation of the mechanisms of some general anesthetics may help the development of new drugs and rational clinical use of the drugs in neonates,infants,and pregnant and parturient women." @default.
- W2372200229 created "2016-06-24" @default.
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- W2372200229 date "2012-01-01" @default.
- W2372200229 modified "2023-09-25" @default.
- W2372200229 title "Effects of some general anesthetics on the development of the central nervous system and their mechanisms" @default.
- W2372200229 hasPublicationYear "2012" @default.
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