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- W2372201590 abstract "Objective To investigate the adverse reactions and treatment of bilirubin adsoption combined with plasma exchange. Methods A total of 316 patients received bilirubin adsorption combined with plasma exchange from March 2012 to August 2014 were enrolled, which included 241 males and 75 females, aged 15- 71 years old with mean age of 40.5 years old.The adverse reactions were analyzed in artificial liver treatment and postoperative treatment. For patients with hypotension, fluid infusion and slowing down blood flow velocity were applied, and treatment were stopped in necessary. For patients with allergic blood plasma, intravenous injection of 10 % calcium gluconate, intravenous injection of dexamethasone or intramuscular injection of promethazine were applied to prevent allergy in necessary. For patients with femoral vein catheters easily occurred plugging,fully heparinization before treatment and pumped into heparin sodium in treatment were applied. And for patients with hypokalemia, intravenous injection of 10 % potassium chloride was applied. Results A total of 316 patients received artificial liver support system treatment for 1 260 times, with mean of 4 times per person. The 182 times(14.4 %) of adverse reaction were recorded. In all of adverse reactions, the most frequently recorded adverse events were hypotension(100 times, 54.9 %), then followed by allergic reaction(43 times, 23.6 %), hypokalemia(30 times, 16.5 %), vomiting(5 times, 2.7 %) and extracorporeal circulation tubes plugging(4 times, 2.2 %). All patients completed treatment by actively treatment of adverse reactions. Conclusion It is demonstrated that enhancing observation and nursing in treatment of artificial liver support system could effectively decrease occurring of adverse reactions and has important significance in improving the treatment efficiency and reducing incidence rate." @default.
- W2372201590 created "2016-06-24" @default.
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- W2372201590 date "2015-01-01" @default.
- W2372201590 modified "2023-09-24" @default.
- W2372201590 title "Adverse reaction and treatment of bilirubin adsorption combined with plasma exchange" @default.
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