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- W2372203030 abstract "To assess the clinical efficacy and hemodynamic effectsof dauricine(Dau) a double blind randomized study, was perfermed in 34patients with frequent ectopic activity at rest. After a baseline evalua-tion, the patients were divided randomly into two groups: In group A,4 weeks of treatment with Dau were followed by one week of treatmentwith placebo. In group B, one week of treatment with placebo wasfollowed by 4 weeks of treatment with Dau. The effective rate at theend of the first week in group A was 71%, but the effective rate at theend of the placebo period in group B was only 6%(P0.01). The totaleffective rate of Dau for two groups was 94.1%. The efficacy of Daudisappeared after one week of treatment with placebo in group A. Hemodynamic changes were measured by impedance cardiogram andsystolic time interval. There were no significant changes in CO, SV,TPR, PEP PEP/LVET and MAP. After 4 weeks of treatment with Dauthere were prolongation in LVET and decrease in HR. These results indicate that Dau is an effective antiarrhythmic drugwithout obvious depression of cardiac function." @default.
- W2372203030 created "2016-06-24" @default.
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- W2372203030 date "1987-01-01" @default.
- W2372203030 modified "2023-09-24" @default.
- W2372203030 title "INVESTIGATION OF CLINICAL EFFICACY AND HEMODYNAMIC EFFECTS OF DAURICINE IN PATIENTS WITH ARRHYTHMIAS" @default.
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