Matches in SemOpenAlex for { <https://semopenalex.org/work/W2372264186> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2372264186 abstract "This study aimed to evaluate the effects of Echinococcus multilocularis(Em) infection on the expressions of TGF-β 1,TGF-β receptors(TβRⅠ and TβRⅡ) and signal proteins(Smad2 and Smad3) in the liver of Balb/c mice.We randomly divided Balb/c mice into an experiment group and a normal control group.The infection model was induced by injecting the Em suspension directly,while the control group was injected with physiological saline.The mice were euthanized and the livers were collected at 60 days.The mRNA of TGF-β1,Smad2,and Smad3 were analyzed by RT-PCR;the protein expression and location of TGF-β1,TβRⅠ,TβRⅡ,and Smad2/3 were analyzed by Western-blot and immunohistochemistry respectively.The level of liver fibrosis and pathological alteration were observed by HE and Masson staining.We found the mRNA and protein expression of TGF-β1 and Smad2,and Smad3 were increased in experiment group,compared to controls.TGF-β1,TβRⅠand Smad2/3 mainly situated in the cytoplasm,while TβRⅡ located in the cell membrane.The expressions of all indexes stated above were significant different between experiment group and control group.All the results showed that the pathway of TGF-β1/Smads signal protein participate the liver fibrosis and hepatic injury in Em-infected Balb/c mice,and the mutualism of host and parasite possibly mediated by the TGF-β1/Smads signal pathway." @default.
- W2372264186 created "2016-06-24" @default.
- W2372264186 creator A5032564504 @default.
- W2372264186 date "2011-01-01" @default.
- W2372264186 modified "2023-09-24" @default.
- W2372264186 title "Effects of Echinococcus multilocularis infection on the expression TGF-β1 and its signal protein in liver of Balb/c mice" @default.
- W2372264186 hasPublicationYear "2011" @default.
- W2372264186 type Work @default.
- W2372264186 sameAs 2372264186 @default.
- W2372264186 citedByCount "0" @default.
- W2372264186 crossrefType "journal-article" @default.
- W2372264186 hasAuthorship W2372264186A5032564504 @default.
- W2372264186 hasConcept C104317684 @default.
- W2372264186 hasConcept C105580179 @default.
- W2372264186 hasConcept C118131993 @default.
- W2372264186 hasConcept C126322002 @default.
- W2372264186 hasConcept C134018914 @default.
- W2372264186 hasConcept C142724271 @default.
- W2372264186 hasConcept C153911025 @default.
- W2372264186 hasConcept C165901193 @default.
- W2372264186 hasConcept C170493617 @default.
- W2372264186 hasConcept C203014093 @default.
- W2372264186 hasConcept C204232928 @default.
- W2372264186 hasConcept C2776225656 @default.
- W2372264186 hasConcept C2776415932 @default.
- W2372264186 hasConcept C2776529007 @default.
- W2372264186 hasConcept C2777123769 @default.
- W2372264186 hasConcept C2779687537 @default.
- W2372264186 hasConcept C2779752401 @default.
- W2372264186 hasConcept C55493867 @default.
- W2372264186 hasConcept C62478195 @default.
- W2372264186 hasConcept C71924100 @default.
- W2372264186 hasConcept C86803240 @default.
- W2372264186 hasConcept C8891405 @default.
- W2372264186 hasConcept C90856448 @default.
- W2372264186 hasConcept C95444343 @default.
- W2372264186 hasConceptScore W2372264186C104317684 @default.
- W2372264186 hasConceptScore W2372264186C105580179 @default.
- W2372264186 hasConceptScore W2372264186C118131993 @default.
- W2372264186 hasConceptScore W2372264186C126322002 @default.
- W2372264186 hasConceptScore W2372264186C134018914 @default.
- W2372264186 hasConceptScore W2372264186C142724271 @default.
- W2372264186 hasConceptScore W2372264186C153911025 @default.
- W2372264186 hasConceptScore W2372264186C165901193 @default.
- W2372264186 hasConceptScore W2372264186C170493617 @default.
- W2372264186 hasConceptScore W2372264186C203014093 @default.
- W2372264186 hasConceptScore W2372264186C204232928 @default.
- W2372264186 hasConceptScore W2372264186C2776225656 @default.
- W2372264186 hasConceptScore W2372264186C2776415932 @default.
- W2372264186 hasConceptScore W2372264186C2776529007 @default.
- W2372264186 hasConceptScore W2372264186C2777123769 @default.
- W2372264186 hasConceptScore W2372264186C2779687537 @default.
- W2372264186 hasConceptScore W2372264186C2779752401 @default.
- W2372264186 hasConceptScore W2372264186C55493867 @default.
- W2372264186 hasConceptScore W2372264186C62478195 @default.
- W2372264186 hasConceptScore W2372264186C71924100 @default.
- W2372264186 hasConceptScore W2372264186C86803240 @default.
- W2372264186 hasConceptScore W2372264186C8891405 @default.
- W2372264186 hasConceptScore W2372264186C90856448 @default.
- W2372264186 hasConceptScore W2372264186C95444343 @default.
- W2372264186 hasLocation W23722641861 @default.
- W2372264186 hasOpenAccess W2372264186 @default.
- W2372264186 hasPrimaryLocation W23722641861 @default.
- W2372264186 hasRelatedWork W2149943578 @default.
- W2372264186 hasRelatedWork W2161905406 @default.
- W2372264186 hasRelatedWork W2376165651 @default.
- W2372264186 hasRelatedWork W2414588517 @default.
- W2372264186 hasRelatedWork W2415560155 @default.
- W2372264186 hasRelatedWork W2885762446 @default.
- W2372264186 hasRelatedWork W2907287499 @default.
- W2372264186 hasRelatedWork W2977868382 @default.
- W2372264186 hasRelatedWork W2985118006 @default.
- W2372264186 hasRelatedWork W3013553465 @default.
- W2372264186 hasRelatedWork W3024570389 @default.
- W2372264186 hasRelatedWork W3029554735 @default.
- W2372264186 hasRelatedWork W3029583932 @default.
- W2372264186 hasRelatedWork W3029765586 @default.
- W2372264186 hasRelatedWork W3030082748 @default.
- W2372264186 hasRelatedWork W3030542001 @default.
- W2372264186 hasRelatedWork W3030693463 @default.
- W2372264186 hasRelatedWork W3031291558 @default.
- W2372264186 hasRelatedWork W3031570653 @default.
- W2372264186 hasRelatedWork W3032265880 @default.
- W2372264186 isParatext "false" @default.
- W2372264186 isRetracted "false" @default.
- W2372264186 magId "2372264186" @default.
- W2372264186 workType "article" @default.