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- W2372346621 abstract "Objectives:To study the value of chemiluminescent microparticle immunoassay(CMIA) in the detection of specific antibodies to Treponema pallidum and to discuss its clinical applicability.Methods:We selected 260 patients who came to our hospital for outpatient and inpatient service from May 2011 to May 2012.Patients' serum was examined with gelling test Treponema pallidum(TPPA) and CMIA method to compare the positive detection rates of the two methods.TPPA was set as a standard to evaluate the sensitivity,specificity,negative predictive value,and positive predictive value of CMIA method.Results: The detection rate of CMIA method is 16.2%,while the rate of TPPA method is 14.6%.There is no statistical difference between the two groups in the positive detection rates(P 0.05).The sensitivity of CMIA method is 100%,specificity 98.2%, positive predictive value 90.5%,and negative predictive value 100%.The consistence rate between CMIA and TPPA method in detecting Treponema pallidum antibodies was 98.7%.Conclusions:The CMIA is characterized by automation,short detection period and can be used in laboratory batch testing for syphilis antibodies.The detection rate of CMIA has no significant difference from that of Treponema pallidum gelling test while its specificity is higher.TPPA in combination with clinical data can be used in the diagnosis of syphilis in clinical settings." @default.
- W2372346621 created "2016-06-24" @default.
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- W2372346621 date "2013-01-01" @default.
- W2372346621 modified "2023-09-23" @default.
- W2372346621 title "Significance of chemiluminescent microparticle immunoassay in detecting treponema pallidum specific antibody" @default.
- W2372346621 hasPublicationYear "2013" @default.
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