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- W2372364343 abstract "Objective To explore the feasibility and value of CEUS in evaluating synovitis of antigen-induced arthritis(AIA) rabbit models.Methods Thirty New Zealand white rabbits were equally divided into group A and group B,and were injected 2 mg and 8 mg ovalbumin,respectively.At the 4th week,two-dimensional ultrasound,CEUS and enhanced MRI were performed to evaluate the severity degree of synovitis.These results of US and MR were compared,and the correlation was analyzed.Results The incidence rate of synovitis and score between group A and group B by both US and MRI were statistically different(both P0.05).The difference of synovitis detection rate and score by CEUS and enhanced MRI had no statistical significance(P0.05).The consistency(Kappa=0.78,P0.05) and correlation(r=0.94,P0.05) for synovitis score between CEUS and MRI were good.Taking the results of MRI as golden standards,the sensitivity,specificity,accuracy rate and Youden index of US and CEUS in the diagnosis of synovitis in AIA model was 72.73%(16/22),97.37%(37/38),88.33%(53/60),0.70 and 90.91%(20/22),100%(38/38),96.67%(58/60),0.91,respectively.Conclusion CEUS can be applied as a new strategy for evaluation of synovitis and following up of the therapy effect in AIA rabbit models." @default.
- W2372364343 created "2016-06-24" @default.
- W2372364343 creator A5042946501 @default.
- W2372364343 date "2013-01-01" @default.
- W2372364343 modified "2023-09-23" @default.
- W2372364343 title "CEUS in evaluating synovitis of antigen-induced arthritis rabbit models" @default.
- W2372364343 hasPublicationYear "2013" @default.
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