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- W2372382158 abstract "Objective To observe the changengs of αvβ3,PDGF and TIMP-1 before and after therapy,by infusing danshen injection into uterine cavity,through such a way to investigate the relationship between danshen injection and IUA,and to elucidate the mechanism of this medicine in preventing and treating IUA.Methods 90 patients were randomly divided into danshen group,viscoelastic solution group and blank control group,30 patients in each group.Observing the changes of αvβ3,PDGF and TIMP-1 before and after therapy,through two-dimensional electrophoresis.Results Three groups had no difference in αvβ3,PDGF and TIMP-1 before therapy(P0.05),while after therapy the PDGF and TIMP-1 expression in blank control group were more than the other two groups(P0.05),but the αvβ3 level was less than the other two groups(P0.05).There were no difference between viscoelastic solution group and danshen group in αvβ3,PDGF and TIMP-1.Conclusion The abnormal expression of αvβ3,PDGF and TIMP-1can proliferate uerine fiber,and participate in development and progression of IUA,danshen injection and viscoelastic solution can reduce IUA rate and increase endometrial receptivity through regulating expression of αvβ3,PDGF and TIMP-1." @default.
- W2372382158 created "2016-06-24" @default.
- W2372382158 creator A5026668267 @default.
- W2372382158 date "2012-01-01" @default.
- W2372382158 modified "2023-09-25" @default.
- W2372382158 title "Effects of danshen injection on αvβ3,PDGF and TIMP-1 in endometrium of patients with moderate to severe intrauterine adhesions" @default.
- W2372382158 hasPublicationYear "2012" @default.
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