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- W2372433308 abstract "Objective To study the the mechanism of malignant transformation induced by CagA gene positive broth culture filtrates of Helicobacter pylori in human gastric epithelial cells. Methods CagA related gene was researched by the mRNA differential display technique using GES 1 cells which they were treated with CagA gene positive and negative broth culture filtrates of Helicobacter pylori . Results The results of mRNA differential display showed that there are significant differences in geng expression between GES 1 cells treated with CagA gene positive and negative filtrates of Hp. The result of dot blotting analysis also was resemble. An isolated clone showed 100% homology with the tRNAs of human mitochondrial genes. Conclusion The effects of malignant transformation induced by CagA in GES 1 cells, is responsible for the progression of tRNAs of human mitochondrial genes." @default.
- W2372433308 created "2016-06-24" @default.
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- W2372433308 date "2001-01-01" @default.
- W2372433308 modified "2023-09-23" @default.
- W2372433308 title "The expression of several tRNAs human mitochondrial genes in human gastric epithelial cells were transformated by CagA gene positive broth culture filtrates of Helicobacter pylori" @default.
- W2372433308 hasPublicationYear "2001" @default.
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