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- W2372437723 abstract "Objective To research the expression of XIAP and Caspase-3 in the occurrence and development of osteosarcoma(Os) and clinical significance.Methods Immunohistochemical method was used to examine the positive expression of XIAP and Caspase-3 in 38 specimens of Os and 10 specimens of chondroma(Oc).Results For the Oc,7 specimens showed positive Caspase-3 expression in 10 negative expression of XIAP was 10 specimens.For the 38 Os,the rate of positive Caspase-3-expression was 18.4 %.The rate of XIAP was 68.4%,the rate of XIAP was significantly higher than that of Oc(P0.05).For the 38 Os,the rate of positive Caspase-3-expression was 18.4%,the positive rate was significantly higher in better-differentiated Os than that in lower-differentiated cases(P0.05).The rate of positive that Caspase-3 or XIAP expressed was not associated with gender,age.There was negative association between the level of Caspase-3 expression and XIAP in Os(P0.05).Conclusion Expression of XIAP is high and expression of Caspase-3 is low in Os;expression of Caspase-3 is high and expression of XIAP is low in Oc;there was negative association between the expression level of Caspase-3 and XIAP in Os." @default.
- W2372437723 created "2016-06-24" @default.
- W2372437723 creator A5078709318 @default.
- W2372437723 date "2010-01-01" @default.
- W2372437723 modified "2023-09-25" @default.
- W2372437723 title "Expression of Caspase-3 and XIAP in osteosarcoma and their clinical significance" @default.
- W2372437723 hasPublicationYear "2010" @default.
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