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- W2372458265 abstract "Objective To investigate the expressions of 5-HT,glucagon,somatostatin and gastrin in gastrointestinal carcinoid and its clinical significance.Methods Immunohistochemistry SP method was used to examine the expressions of the four hormonal proteins in 36 cases of gastrointestinal carcinoid.Results The positive rates of the gastrin increased in the poor differentiated gastrointestinal carcinoid tissues(P0.05).The expression of gastrin was related to the metastasis of lymph node in gastrointestinal carcinoid tissues(P0.05).The expression of the somatostatin was associated with the stage of tumor,the positive rates of somatostatin decreased in the lymph node metastasis of gastrointestinal carcinoid(P0.01).5-HT and glucagon had no correlation with the differentiation and lymph node metastasis of carcinoid(P0.05).Conclusion When gastrin and somatostatin combine with the membrane receptor of cell,they can stimulate or inhibit the proliferation of the tumor cells.These data indicate that the hormonal proteins may be valuable markers to predict the biologic behavior and prognosis in gastrointestinal carcinoid." @default.
- W2372458265 created "2016-06-24" @default.
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- W2372458265 date "2007-01-01" @default.
- W2372458265 modified "2023-09-27" @default.
- W2372458265 title "The correlation between the expressions of gastrin,somatostatin and the metastasis of lymph node in gastrointestinal carcinoid" @default.
- W2372458265 hasPublicationYear "2007" @default.
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