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- W2372470720 abstract "Objective To establish alcoholic fatty liver model with alcohol and fat emulsion in rats.Methods Sixty SD male rats were randomly divided into NS(intragastric infusion of saline,5 ml/kg,fed with common diet),HM and LM groups(intragastric infusion of alcohol by 60%V/V or 30%V/V,5 ml/kg,fed with intralipid,5 ml/kg).Half of rats were sacrificed after 2 w to evaluate the process of alcoholic fatty liver formation.All rats were sacrificed at the end of the third week.The pathologic of the liver and the biochemistry index of plasma were observed.Results Slight fatty deposition was observed at the end of the 2nd week after experiment,and 3 weeks later,severe fatty deposition appeared.The levels of serum TG,CH,ALT and AST of HM and LM groups were higher than those of NS group(P0.05).Conclusions The lesion of the alcoholic fatty liver model in rats is similar to that in humans.The experiment is very simple and the experiment cycle is short and the conclusion is clear." @default.
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- W2372470720 date "2011-01-01" @default.
- W2372470720 modified "2023-09-25" @default.
- W2372470720 title "Establishing alcoholic fatty liver model with alcohol and fat emulsion in rats" @default.
- W2372470720 hasPublicationYear "2011" @default.
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