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- W2372493664 abstract "Objective: To study the effect of Zhongtongxiao cataplasma on the expression of tumour necrosis factor- α( TNF- α) in the rat model of lumbar disc herniation( LDH). Methods: Forty- eight experimental rats were randomly and equally divided into normal group,model group,Zhongtongxiao cataplasma group,and dogskin plaster group. All rats except those in normal group were treated by pressing the nucleus pulposus to establish a rat model of LDH. The Zhongtongxiao cataplasma group and dogskin plaster group received treatment with Zhongtongxiao cataplasma and dogskin plaster,respectively. On the 7th,14th,and 21st days after the model was successfully established,the content of TNF- α in the tissue around the nerve root was determined and then compared between the two groups. Results: The model group had a significantly increased TNF- α content compared with the normal group( P 0. 01). The Zhongtongxiao cataplasma group and dogskin plaster group had significantly reduced TNF- α content compared with the model group( P 0. 05),and the Zhongtongxiao cataplasma group had a significantly higher reduction than the dogskin plaster group( P 0. 05). Conclusion: Zhongtongxiao cataplasma can significantly inhibit the increase in the content of TNF- α in the tissue around the nerve root among rats with LDH." @default.
- W2372493664 created "2016-06-24" @default.
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- W2372493664 date "2014-01-01" @default.
- W2372493664 modified "2023-09-25" @default.
- W2372493664 title "Effect of Zhongtongxiao cataplasma on TNF-α expression in rat model of lumbar disc herniation" @default.
- W2372493664 hasPublicationYear "2014" @default.
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