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- W2372505094 abstract "Objective To investigate the changes of serum sexual hormone levels in the rats exposed to cadmium by drinking water. Methods Cadmium was given to rats at 0,50,100 and 200 mg/kg in drinking water.The serum testosterone,follicle stimulating hormone,and luteinizing hormone were determined by radioimmunoassay. Results At the end of the first month with cadmium administration,there was no significant change in serum hormone levels.At the end of the third month after cadmium administration,the levels of serum testosterone in the 50,100 and 200 mg/kg groups were 286.88,225.63 and 259.60 pmol/L,respectively,which were significantly higher than that in control group(111.58 pmol/L).At the end of the sixth month,however,significant elevation of serum testosterone could only be observed in the Cd exposure group at 200 mg/kg(327.34 pmol/L).In the meantime,a significant decrease of luteinizing hormone was noted in the dose group of 200 mg/kg(2.53 ng/ml) when compared with the control group(4.52 ng/ml) in the sixth month after cadmium administration. Conclusion Oral exposure to cadmium may induce change in the levels of serum testosterone and luteinizing hormone." @default.
- W2372505094 created "2016-06-24" @default.
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- W2372505094 date "2001-01-01" @default.
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- W2372505094 title "Effects of cadmium on serum sexual hormones in rats" @default.
- W2372505094 hasPublicationYear "2001" @default.
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