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- W2372517097 abstract "AIM:To explore the characteristic of changes of polysomnography (PSG) between insomnia patients with depression and normal people.To assess the effects and varieties of PSG with trazodone. METHODS:Polysmith PSG was performed on 21 insomnia patients with depression and 10 normal people. Insomnia patients with depression were cared with trazodone and PSG was undertaken again two months later. Efficacies were assessed using the self-rating depression (SDS) and the Hamilton anxiety scale (HAMA) before and at the end of the second month treatment.Data were figured by(?)±s and analized by SPSS 11.0 software.RESULTS:After trazodone treatment,PSG showed:total sleep time prolonged (350±s 30) min in comparing with (393±27) min,P0.01;sleep efficiency index increased (74.0±2.0) % comparing with (86±4)%,P0.05;wake-up onset after sleep shortened (82±7) min comparing with (19±5) min, P0.01;REM time reduced (107±13) min comparing with (98±7) min,P0.01;S2 time decreased (189±5) min comparing with (181±4) min,P0.05;non-REM slow-wave sleep prolonged (40±3) min comparing with (69.0±2.0) min,P0.01;no significant difference in sleep latent period,REM latency, REM times and S1 time (P0.05).SDS and HAMA were better.CONCLUSION:Insomnia patients with depression had abnormal PSG would be effected by trazodone treatment and also good to abnormal night physiological signals on PSG.Trazodone caused an improvement in subjective and objective sleep quality." @default.
- W2372517097 created "2016-06-24" @default.
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- W2372517097 date "2007-01-01" @default.
- W2372517097 modified "2023-09-26" @default.
- W2372517097 title "Study on effects and varieties of polysomnography in insomnia patients with depression cared with trazodone" @default.
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