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- W2372538029 abstract "Objective To investigate clinical significance of change in level of serum 25-hydroxy vitamin D in diabetic patients with acute coronary syndrome.Methods From Jul.2006to Oct.2008,27diabetic patients admitted to General Hospital of Beijing Military Command were enrolled as DM group,52patients with acute coronary syndrome(ACS)as ACS group in whom 31were with unstable angina pectoris(UAP)and the other 21were with acute myocardium infarct(AMI),46diabetic patients complicating ACS as DM+ACS group in whom 20patients were complicated with AMI(DM+AMI)and the other 26patients with UAP(DM+UAP),and 28health volunteers served as normal control group.Serum 25-hydroxy vitamin D and calcium levels were measured by automatic biochemical analyzer.C-reactive protein(CRP),matrix metalloproteinase-9(MMP-9)and heparanase(HPA)in serum were measured by ELISA.The correlations between serum 25-hydroxy vitamin D and calcium,CRP,MMP-9,HPA were analyzed.Results The serum level of 25-hydroxy vitamin D was significantly lower in DM+ACS group than in ACS group,DM group and normal control group,and it was significantly lower in DM+AMI subgroup than in DM+UAP subgroup.A positive correlation was found between the levels of 25-hydroxy vitamin D and calcium.No significant relationship was found between the serum levels of 25-hydroxy vitamin D and CRP,MMP-9or HPA.Conclusion Serum 25-hydroxy vitamin D in diabetic patients with ACS shows a decreasing tendency,which may have relationship with the increase in CRP,MMP-9and HPA." @default.
- W2372538029 created "2016-06-24" @default.
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- W2372538029 date "2010-01-01" @default.
- W2372538029 modified "2023-09-27" @default.
- W2372538029 title "Change in serum 25-hydroxy vitamin D and its significance in diabetic patients with acute coronary syndrome" @default.
- W2372538029 hasPublicationYear "2010" @default.
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