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- W2372604837 abstract "Objective: To investigate the relationship between apoptosis,NSE,and neurological impairment in perihematoma in experimental intracerebral hemorrhage in rats.Methods: Intracerebral hemorrhage was induced in rats by injection of bacterial collagenase into the caudate nucleus.Histopathological changes,TUNEL,Neuron specific enolase(NSE) immunohistochemistry results and neurologicl impairment were studied in 6 h,12 h,24 h,48 h,72 h,5 d,7 d after the injection.Results: Neurological impairment occurred in each rat after cerebral hemorrhage,and the most severe neurological impairment was found at 24-48 h after injection.TUNEL positive cells were found at 6 h after injection first,most evident at 48 h after injection.NSE leaked from the neuron reached the peak also at the 48 h after injection.Conclusion: The apoptosis may relate to the degree of the neurologic impairment and the NSE changes.Apoptosis may play an important role in neurological impairment after cerebral hemorrhage." @default.
- W2372604837 created "2016-06-24" @default.
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- W2372604837 date "2010-01-01" @default.
- W2372604837 modified "2023-09-24" @default.
- W2372604837 title "The Relationship between Apoptosis,NSE,and Neurological Impairment in Experimental Intracerebral Hemorrhage in Rats" @default.
- W2372604837 hasPublicationYear "2010" @default.
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