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- W2372611648 abstract "Objective To establish a HPLC method for determination of triacetyl-ganciclovir and provide the basis for enterprises to decide wehther the triacetyl-ganciclovir should be recycled or not. Methods Triacetyl-ganciclovir was diluted with mobile phase for high performance liquid chromatography(HPLC) analysis. The chromatography was performed on a COSMOSIL 5C18-PAQ Packed Column(4. 6 mm × 250 mm,5 μm) with methanol-water(10∶90) as the mobile phase. The eluent was detected at 255 nm with 25 ℃ of column temperature. Results The regression equation was ΔA = 1156C(μg / m L)-262(r = 0. 9999),linear range was 1-40 μg / m L,and the LOQ was 1 μg / m L with good precision(RSD = 0. 6%) and repeatability(RSD = 0. 2%). The concentration of triacetyl-ganciclovir was 23. 2 μg / m L in mother liquor. Conclusion The HPLC method for determination of triacetyl-ganciclovir is simple and accurate with high sensitivity and repeatability." @default.
- W2372611648 created "2016-06-24" @default.
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- W2372611648 date "2014-01-01" @default.
- W2372611648 modified "2023-09-23" @default.
- W2372611648 title "Quantitative analysis of triacetyl-ganciclovir by HPLC" @default.
- W2372611648 hasPublicationYear "2014" @default.
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