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- W2372675385 abstract "Objective YunKe is a kind of multiple preparation with the bisphosphonate and microelement.To study the regulation of YunKe in Bone Metabolism by following 113 patients with postmenopausal osteoporosis in 9th month after therapy.Method To observe the effects of Yunke on the serum IL-1,IL-6,TNF-α,BGP,BALP,E_2 and bone mineral density(BMD) in 113 patients diagnosed as postmenopausal osteoporosis.Result Before medication,BMD and the level of serum E_2 significantly decreased(P0.01),and the levels of serum IL-1,IL-6 BALP,BGP significantly increased(P0.01).The level of TNF-αwas higher than that in control group(P0.05).The levels of serum IL-1,IL-6,BALP,BGP decreased rapidly in the 9th month after therapy,while BMD increased(P0.05).There was no change on the level of serum E_2.Conclusion YunKe plays an obvious orientation role in bone formation area,and regulates bone metabolism after entering the bone tissue.It can restrain the activity of osteoclast and the loss of bone,and increase BMD." @default.
- W2372675385 created "2016-06-24" @default.
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- W2372675385 date "2008-01-01" @default.
- W2372675385 modified "2023-09-27" @default.
- W2372675385 title "The regulation of YunKe in bone metabolism of postmenopausal osteoporosis" @default.
- W2372675385 hasPublicationYear "2008" @default.
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