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- W2372681801 abstract "Objective To Explore the effect of DMSO and TPA on the proliferation and morphology and ultrastructure of human lung carcinoma cell line GLC. Methods The changes of the proliferation and morphology and ultrastructure of GLC cell line treated by DMSO were observed by optical microscope, scanning electron microscope, and transmission electron microscope. Results Having been treated by DMSO and TPA, the proliferation of GLC cells was inhibited, the morphology of GLC cells became consistent, the volume of cells increased, the nucleo cytoplasmic ratio decreased, the number of nucleolus decreased, microvill on the surface of cells and filopodia on the edge of cells reduced, sheed pseudopodia increased, the shape of nuclear was regular, heterochromatin decreased, euchromatin increased, the number of cell apparatus increased, and the structure of cell apparatus was turning to normal.Conclusion DMSO and TPA changed the malignant morphology and ultrastructure characteristics of GLC and had inducing differentiation effects on GLC cells [" @default.
- W2372681801 created "2016-06-24" @default.
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- W2372681801 date "2003-01-01" @default.
- W2372681801 modified "2023-09-25" @default.
- W2372681801 title "OBSERVATION ON ULTRASTRUCTURE AND MORPHOLOGY OF GLC CELLS DURING INDUCING DIFFERENTIATION BY TPA AND DMSO" @default.
- W2372681801 hasPublicationYear "2003" @default.
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