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• W2372703229 abstract "Background & Aims The outputs of physiological systems fluctuate in a complex manner even under resting conditions. Decreased variability or increased regularity of these outputs is documented in several disease states. Changes are observed in the spatial and temporal configuration of the electroencephalogram (EEG) in patients with hepatic encephalopathy (HE), but there is no information on the variability of the EEG signal in this condition. The aim of this study was to measure and characterize EEG variability in patients with cirrhosis and to determine its relationship to neuropsychiatric status. Methods Eyes-closed, awake EEGs were obtained from 226 patients with cirrhosis, classified, using clinical and psychometric criteria, as neuropsychiatrically unimpaired (n = 127) or as having minimal (n = 21) or overt (n = 78) HE, and from a reference population of 137 healthy controls. Analysis of EEG signal variability was undertaken using continuous wavelet transform and sample entropy. Results EEG variability was reduced in the patients with cirrhosis compared with the reference population (coefficient of variation: 21.2% [19.3–23.4] vs. 22.4% [20.8–24.5]; p <0.001). A significant association was observed between EEG variability and neuropsychiatric status; thus, variability was increased in the patients with minimal HE compared with their neuropsychiatrically unimpaired counterparts (sample entropy: 0.98 [0.87–1.14] vs. 0.83 [0.75–0.95]; p = 0.02), and compared with the patients with overt HE (sample entropy: 0.98 [0.87–1.14] vs. 0.82 [0.71–1.01]; p = 0.01). Conclusions Variability of the EEG is associated with both the presence and severity of HE. This novel finding may provide new insights into the pathophysiology of HE and provide a means for monitoring patients over time. Lay summary Decreased variability or increased regularity of physiological systems is documented in several disease states. Variability of the electroencephalogram was found to be associated with both the presence and severity of brain dysfunction in patients with chronic liver disease. The outputs of physiological systems fluctuate in a complex manner even under resting conditions. Decreased variability or increased regularity of these outputs is documented in several disease states. Changes are observed in the spatial and temporal configuration of the electroencephalogram (EEG) in patients with hepatic encephalopathy (HE), but there is no information on the variability of the EEG signal in this condition. The aim of this study was to measure and characterize EEG variability in patients with cirrhosis and to determine its relationship to neuropsychiatric status. Eyes-closed, awake EEGs were obtained from 226 patients with cirrhosis, classified, using clinical and psychometric criteria, as neuropsychiatrically unimpaired (n = 127) or as having minimal (n = 21) or overt (n = 78) HE, and from a reference population of 137 healthy controls. Analysis of EEG signal variability was undertaken using continuous wavelet transform and sample entropy. EEG variability was reduced in the patients with cirrhosis compared with the reference population (coefficient of variation: 21.2% [19.3–23.4] vs. 22.4% [20.8–24.5]; p <0.001). A significant association was observed between EEG variability and neuropsychiatric status; thus, variability was increased in the patients with minimal HE compared with their neuropsychiatrically unimpaired counterparts (sample entropy: 0.98 [0.87–1.14] vs. 0.83 [0.75–0.95]; p = 0.02), and compared with the patients with overt HE (sample entropy: 0.98 [0.87–1.14] vs. 0.82 [0.71–1.01]; p = 0.01). Variability of the EEG is associated with both the presence and severity of HE. This novel finding may provide new insights into the pathophysiology of HE and provide a means for monitoring patients over time." @default.
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• W2372703229 date "2016-09-01" @default.
• W2372703229 modified "2023-09-26" @default.
• W2372703229 title "Electroencephalogram variability in patients with cirrhosis associates with the presence and severity of hepatic encephalopathy" @default.
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• W2372703229 cites W2011317006 @default.
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• W2372703229 cites W2026352845 @default.
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• W2372703229 cites W2049270581 @default.
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• W2372703229 cites W2058690021 @default.
• W2372703229 cites W2060123467 @default.
• W2372703229 cites W2072139861 @default.
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• W2372703229 doi "https://doi.org/10.1016/j.jhep.2016.05.004" @default.
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