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- W2372720400 abstract "Objective To establish quick and easy detection methods of pantolactone and pantoic acid,and study autohydrolysis status of DL-pantolactone during enzymatic resolution.Methods Pantolactone and pantoic acid were detected by using silica gel thin-layer chromatography with iodine vapor as a color developing agent;a new polarimetric method was established for the evaluation of enzymatic resolution reaction degree of DL-pantolactone by HPLC and the effect of pH in DL-pantolactone's autohydrolysis was studied.Results and Conclusions The methods of thin-layer chromatography and polarimetry are suitable for enzymatic resolution of DL-pantolactone reaction quick detection;DL-pantolactone's autohydrolysis increases with the increase of pH values;at a certain pH value,the autohydrolysis increases with the prolongation of the time duration." @default.
- W2372720400 created "2016-06-24" @default.
- W2372720400 creator A5065442308 @default.
- W2372720400 date "2009-01-01" @default.
- W2372720400 modified "2023-09-28" @default.
- W2372720400 title "Detection methods of enzymatic resolution process on DL-pantolactone and its autohydrolysis" @default.
- W2372720400 hasPublicationYear "2009" @default.
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