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- W2372721794 abstract "Objective To explore the protective effect of lyceum seedoil on cognitive injury induced by chronil hypoperfusion of the brain in rats.Methods Chronic hypoperfusion model of the brain injury was established in SD rats by bilateral common carotid artery occlusion.Rats were randomly divided into high-dosage group with 0.8mL·100g-1,middle-dosage group with 0.4mL·100g-1 and low-dosage group with 0.2mL·100g-1.After the drug groups were fed up for 60 days,the morris water maze experiment was carried out to test the ability of memory through septohippocampus.The content of ChAT and activity of TChE were determined in rats hippocampi and cortical tissue.Results ①The dosage groups all had improvement effect on the learning and memory disturbance of rats.②The activity of TChE was significantly reduced and ChAT was significantly increased in brain tissue of the cure group.Conclusion Lyceum seedoil can alleviate the rat cognitive dysfunction induced by chronic cerebral ischemia and inhibit the activity of TchE in functional areas of the brain,also increase the activity of ChAT." @default.
- W2372721794 created "2016-06-24" @default.
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- W2372721794 date "2011-01-01" @default.
- W2372721794 modified "2023-09-28" @default.
- W2372721794 title "Protective Effect of Lyceum Seedoil on Cognitive Injury Induced by Chronil Hypoperfusion of the Brain in Rats" @default.
- W2372721794 hasPublicationYear "2011" @default.
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