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- W2372796577 abstract "AIM:To investigate the effects of Lanthanum chloride (LaCl3 ) on regulatory axis of growth hormone (GH)secretion. METHODS: Measuring GH contents in pituitary slices cultured with radioimmunoassay, and measuring monoamine neurotransmitter contents in hypothalamic slice cultured with florescence analysis. RESULTS: GH content in pituitary slice culture was higher in 0.01 mmol/L LaCl3 group and was lower in 1 mmol/L group than that of the control group(P 0.01 ). The GH contents in pituitary and hypothalamic slice culture was higher in 0.01 mmol/L LaCl3 than that of control group or the single pituitary group (P 0.01 ), but there was no obvious changes in 1 mmol/L LaCl3 group compared with control group (P 0.01). In hypothalamic culture, NE content was higher and 5 - HT content was lower in 0.01 mmol/L LaCl3 and was lower than that of control group. In 1 mmol/L LaCl3 group, NE content was lower, 5- HT was higher than that of control. CONCLUION: Lower LaCl3 dose can act on both hypothalamus and hpophysis and elevated the GH levelin culture directly and indirectly." @default.
- W2372796577 created "2016-06-24" @default.
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- W2372796577 date "1999-01-01" @default.
- W2372796577 modified "2023-09-25" @default.
- W2372796577 title "Study of effects of LaCl_3 on regulatory axis of growth hormone secretion in vitro" @default.
- W2372796577 hasPublicationYear "1999" @default.
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