Matches in SemOpenAlex for { <https://semopenalex.org/work/W2372903478> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2372903478 endingPage "60" @default.
- W2372903478 startingPage "956" @default.
- W2372903478 abstract "To investigate the effect of transfusion of necrotic cells on regulatory T (Treg) and Th17 cell balance in septic mice.Thirty-four C57BL/6 mice were randomized into PBS group (n=5), sham-operated group (n=5), sepsis group (n=12), and necrotic cell transfusion group (n=12) and subjected to intraperitoneal PBS injection, sham operation by separating the cecum only, cecal ligation and puncture (CLP), and injection of 2 × 10⁷ necrotic cells 5 days before CLP, respectively. All the mice were sacrificed 2 weeks after CLP for analyzing the proportion of CD4⁺Foxp3⁺Treg cells and CD4⁺IL17A⁺Th17 cells in the peripheral blood, spleen and thymus by flow cytometry.The percentage of Th17 cells and Treg/Th17 ratio in the spleen was significantly higher in CLP group than in the sham-operated group and PBS group (P<0.01). The percentage of Treg cells in the thymus was significantly lower in CLP group than in the sham-operated group (P<0.01). Pre-infusion of necrotic cells redressed the abnormality of Treg and Th17 cell percentages and Treg/Th17 imbalance in mice following CLP (P<0.05).Pre-infusion of necrotic cells can reverse Treg/Th17 imbalance in septic mice." @default.
- W2372903478 created "2016-06-24" @default.
- W2372903478 creator A5029453738 @default.
- W2372903478 creator A5032443397 @default.
- W2372903478 creator A5054552990 @default.
- W2372903478 creator A5075499010 @default.
- W2372903478 date "2014-06-01" @default.
- W2372903478 modified "2023-09-25" @default.
- W2372903478 title "[Transfusion of necrotic cells redresses regulatory T cell and Th17 cell imbalance in septic mice]." @default.
- W2372903478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25057063" @default.
- W2372903478 hasPublicationYear "2014" @default.
- W2372903478 type Work @default.
- W2372903478 sameAs 2372903478 @default.
- W2372903478 citedByCount "0" @default.
- W2372903478 crossrefType "journal-article" @default.
- W2372903478 hasAuthorship W2372903478A5029453738 @default.
- W2372903478 hasAuthorship W2372903478A5032443397 @default.
- W2372903478 hasAuthorship W2372903478A5054552990 @default.
- W2372903478 hasAuthorship W2372903478A5075499010 @default.
- W2372903478 hasConcept C126322002 @default.
- W2372903478 hasConcept C137061746 @default.
- W2372903478 hasConcept C1491633281 @default.
- W2372903478 hasConcept C16685009 @default.
- W2372903478 hasConcept C179437574 @default.
- W2372903478 hasConcept C202751555 @default.
- W2372903478 hasConcept C203014093 @default.
- W2372903478 hasConcept C2776090121 @default.
- W2372903478 hasConcept C2777507495 @default.
- W2372903478 hasConcept C2778296632 @default.
- W2372903478 hasConcept C2778384902 @default.
- W2372903478 hasConcept C2779727006 @default.
- W2372903478 hasConcept C2780931953 @default.
- W2372903478 hasConcept C3020684253 @default.
- W2372903478 hasConcept C54355233 @default.
- W2372903478 hasConcept C553184892 @default.
- W2372903478 hasConcept C55493867 @default.
- W2372903478 hasConcept C71924100 @default.
- W2372903478 hasConcept C79484868 @default.
- W2372903478 hasConcept C86803240 @default.
- W2372903478 hasConcept C8891405 @default.
- W2372903478 hasConceptScore W2372903478C126322002 @default.
- W2372903478 hasConceptScore W2372903478C137061746 @default.
- W2372903478 hasConceptScore W2372903478C1491633281 @default.
- W2372903478 hasConceptScore W2372903478C16685009 @default.
- W2372903478 hasConceptScore W2372903478C179437574 @default.
- W2372903478 hasConceptScore W2372903478C202751555 @default.
- W2372903478 hasConceptScore W2372903478C203014093 @default.
- W2372903478 hasConceptScore W2372903478C2776090121 @default.
- W2372903478 hasConceptScore W2372903478C2777507495 @default.
- W2372903478 hasConceptScore W2372903478C2778296632 @default.
- W2372903478 hasConceptScore W2372903478C2778384902 @default.
- W2372903478 hasConceptScore W2372903478C2779727006 @default.
- W2372903478 hasConceptScore W2372903478C2780931953 @default.
- W2372903478 hasConceptScore W2372903478C3020684253 @default.
- W2372903478 hasConceptScore W2372903478C54355233 @default.
- W2372903478 hasConceptScore W2372903478C553184892 @default.
- W2372903478 hasConceptScore W2372903478C55493867 @default.
- W2372903478 hasConceptScore W2372903478C71924100 @default.
- W2372903478 hasConceptScore W2372903478C79484868 @default.
- W2372903478 hasConceptScore W2372903478C86803240 @default.
- W2372903478 hasConceptScore W2372903478C8891405 @default.
- W2372903478 hasIssue "7" @default.
- W2372903478 hasLocation W23729034781 @default.
- W2372903478 hasOpenAccess W2372903478 @default.
- W2372903478 hasPrimaryLocation W23729034781 @default.
- W2372903478 hasRelatedWork W1507822347 @default.
- W2372903478 hasRelatedWork W2035920188 @default.
- W2372903478 hasRelatedWork W2358274532 @default.
- W2372903478 hasRelatedWork W2370565999 @default.
- W2372903478 hasRelatedWork W2372903478 @default.
- W2372903478 hasRelatedWork W2387647611 @default.
- W2372903478 hasRelatedWork W3005986839 @default.
- W2372903478 hasRelatedWork W3142726861 @default.
- W2372903478 hasRelatedWork W3145336933 @default.
- W2372903478 hasRelatedWork W4283171337 @default.
- W2372903478 hasVolume "34" @default.
- W2372903478 isParatext "false" @default.
- W2372903478 isRetracted "false" @default.
- W2372903478 magId "2372903478" @default.
- W2372903478 workType "article" @default.