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- W2372911704 abstract "Phenolic compounds including nonylphenol,octylphenol,2,4-dichlorophenol and bisphenol A are widely concerned due to their endocrine disrupting activity and carcinogenicity.Taking Ruditapes philippinarum as an experimental species,this paper studies the activities of antioxidant and detoxification enzymes including superoxide dismutase(SOD),catalase(CAT) and glutathione S-transferase(GST) in gill and visceral tissues in response to the exposure of these four phenolic chemicals.The results showed that the activities of SOD,CAT and GST did not change significantly under exposure to low concentrations of nonylphenol(0.05~0.2 mg/L).The enzyme activities were,however,significantly inhibited under a high dose(0.4 mg/L) with an inhibition rate of 56.6%,59.0% and 35.5% respectively.Within the experimental concentration range(0.05~0.4 mg/L),dichlorophenol inhibited the visceral CAT activity significantly and bisphenol A inhibited the gill GST activity significantly.The three enzymes showed a dose response change in response to phenolic exposure,therefore,they could be adopted as biomarkers indicating phenolic pollution in aquatic environment." @default.
- W2372911704 created "2016-06-24" @default.
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- W2372911704 date "2012-01-01" @default.
- W2372911704 modified "2023-09-25" @default.
- W2372911704 title "Effects of Phenolic Compounds on Enzyme Activities of Antioxidant and Detoxification Systems in Ruditapes philippinarum" @default.
- W2372911704 hasPublicationYear "2012" @default.
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