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- W2372912041 abstract "Objective To improve the appearance and function of the grafted site and meanwhile reduce the scarring of the donor site. Methods An acellular dermal matrix with intact basement membrane complex and normal collagen bundle structure and arrangement was prepared and grafted to the eschar excised burn wounds in four patients. An overlying thin split thickness autograft was placed simultaneously. Results No rejection to this composite skin graft was observed. It was found that after epithelialization of the wound was complete, the transplanted mesh or small stamps of autografts formed a continuous sheet and lost their previous patterns. Thicker and special desquamation appeared on the composite graft site of large sheet of autograft with allograft dermal matrix. All of these phenomena reflected the specialty of the healing processes. It was demonstrated by light and transmission electron microscopy that the desmosome between the spinous cells is clear and the basement membrane is continuous and intact in the composite graft site. In comparison with the control site, the composite skin graft has less contracture, less scarring and better elasticity. Conclusion Through the observation of 3 to 4 months so far, thin split thickness autograft with the acellular dermal matrix was equivalent to or even better than simple split thickness autograft in respect to the appearance and function." @default.
- W2372912041 created "2016-06-24" @default.
- W2372912041 creator A5082060071 @default.
- W2372912041 date "2001-01-01" @default.
- W2372912041 modified "2023-09-25" @default.
- W2372912041 title "The clinical application of composite transplantation of acellular dermal matrix with autograft" @default.
- W2372912041 hasPublicationYear "2001" @default.
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