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- W2372913054 abstract "Objective To investigate the significance of plasminogen activator(tPA) and plasminogen activator inhibitor-1(PAI-1)in acute pulmonary thromboembolism(APE).Methods The levels of PAI-1 and tPA were measured by a commercially available enzyme-linked immunosorbent assay(ELISA)in 44 APE patients and 56 health control persons.Results Compared with tPA 11.05 ng/ml and PAI-1 antigen 61.31 ng/ml in healthy control group,APE patients had higher levels of tPA antigen 33.88 ng/ml and PAI-1 antigen 111.50 ng/ml.In the diagnosis of pulmonary thromboembolism,tPA 21.7 ng/ml and PAI-1 79.4 ng/ml were the cut-off points.Conclusion Increased PAI-1 level in plasma may cause APE.The determination of tPA and PAI-1 concentrations in plasma plays an important role in the diagnosis of APE." @default.
- W2372913054 created "2016-06-24" @default.
- W2372913054 creator A5089086464 @default.
- W2372913054 date "2005-01-01" @default.
- W2372913054 modified "2023-09-23" @default.
- W2372913054 title "Value of measuring plasma concentration of plasminogen activator and its inhibitor-1 in acute pulmonary thromboembolism" @default.
- W2372913054 hasPublicationYear "2005" @default.
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