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- W2372914787 abstract "OBJECTIVE:To investigate the effect of modified technique of total body irradiation (TBI) with high energy X-ray of accelerator on interstitial pneumonia after hematopoietic stem cell transplantation(HSCT). METHODS:Twenty-eight consecutive patients received HSCT. All the patients received CY+TBI±Vp-16 as conditioning regimen. The combination of fractionated TBI and lung blocks were used in all 28 patients to minimize IP as TBI techniques (TBI total dose to 12 Gy, 2 Gy twice a day for 3 days,lung dose to 8.5 Gy). Absorbed doses and the dose distribution within the patient were mearsured by using TLD methods in 19 patients.RESULTS: With a median follow-up of 75 months (24-104 months), 5-year overall survival (OS) was (53.6±9.4)%. 5-year relapse free survival (RFS) was (71.1±8.6)%. The median absorbed doses in region of lung and umbilicus monitored by TLD methods in 19 cases were 8.44 and 11.87 Gy while TBI dose variability within the patient was less than ±10%. None of 28 patients developed interstitial pneumonia. CONCLUSION: The combination of lung blocks and TLD methods in fractionated total body irradiation is effective in reducing interstitial pneumonia." @default.
- W2372914787 created "2016-06-24" @default.
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- W2372914787 date "2008-01-01" @default.
- W2372914787 modified "2023-09-24" @default.
- W2372914787 title "Effects of modified TBI technique on interstitial pneumonia after hematopoietic stem cell transplantation" @default.
- W2372914787 hasPublicationYear "2008" @default.
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