Matches in SemOpenAlex for { <https://semopenalex.org/work/W2372974242> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2372974242 endingPage "23" @default.
- W2372974242 startingPage "21" @default.
- W2372974242 abstract "Objective To investigate the effects of p,p'-DDE on caspase in testis of prepubertal male rats.Methods Twenty male rats(22-day old) were randomly divided into 4 groups,given different concentrations of p,p'-DDE(0,20,60 and 100 mg/kg respectively) in corn oil once every other day by intraperitoneal injection for 10 days,and the volume of injection was 10 ml/kg.After 10 days of treatment,the rats were sacrificed and the organs were weighted,then the testes homogenates were prepared.The mRNA expressions of caspase-3,-8,-9 were determined by real time-PCR,and the activities of caspase-3,-8,-9 were measured with the protocol of assay kit.Results Compared with the control group,no significant changes were seen in body weight,organ coefficient of testes,kidney,spleen and lung,but organ coefficient of liver was increased in group of 100 mg/kg p,p'-DDE.The mRNA expressions of caspase-3,-8,-9 in group of 100 mg/kg p,p'-DDE and caspase-9 in group of 60 mg/kg p,p'-DDE were higher than those of the control group(P0.05).The activities of caspase-3,-8,-9 were increased in group of 100 mg/kg p,p'-DDE(P0.05).Conclusion p,p'-DDE can induce the apoptosis of rat testis through activation of caspase-3 mediated by cleavage of caspase-8 and-9." @default.
- W2372974242 created "2016-06-24" @default.
- W2372974242 creator A5013938837 @default.
- W2372974242 creator A5068855017 @default.
- W2372974242 creator A5077315942 @default.
- W2372974242 date "2010-01-01" @default.
- W2372974242 modified "2023-09-23" @default.
- W2372974242 title "Effects of p,p'-DDE on mRNA Expression and Activity of Caspase in Testis of Prepubertal Male Rats" @default.
- W2372974242 hasPublicationYear "2010" @default.
- W2372974242 type Work @default.
- W2372974242 sameAs 2372974242 @default.
- W2372974242 citedByCount "0" @default.
- W2372974242 crossrefType "journal-article" @default.
- W2372974242 hasAuthorship W2372974242A5013938837 @default.
- W2372974242 hasAuthorship W2372974242A5068855017 @default.
- W2372974242 hasAuthorship W2372974242A5077315942 @default.
- W2372974242 hasConcept C104317684 @default.
- W2372974242 hasConcept C105580179 @default.
- W2372974242 hasConcept C123765429 @default.
- W2372974242 hasConcept C12519072 @default.
- W2372974242 hasConcept C126322002 @default.
- W2372974242 hasConcept C134018914 @default.
- W2372974242 hasConcept C16685009 @default.
- W2372974242 hasConcept C185592680 @default.
- W2372974242 hasConcept C190283241 @default.
- W2372974242 hasConcept C2778206080 @default.
- W2372974242 hasConcept C2780091579 @default.
- W2372974242 hasConcept C2780159080 @default.
- W2372974242 hasConcept C2780931953 @default.
- W2372974242 hasConcept C31573885 @default.
- W2372974242 hasConcept C55493867 @default.
- W2372974242 hasConcept C71924100 @default.
- W2372974242 hasConcept C86803240 @default.
- W2372974242 hasConceptScore W2372974242C104317684 @default.
- W2372974242 hasConceptScore W2372974242C105580179 @default.
- W2372974242 hasConceptScore W2372974242C123765429 @default.
- W2372974242 hasConceptScore W2372974242C12519072 @default.
- W2372974242 hasConceptScore W2372974242C126322002 @default.
- W2372974242 hasConceptScore W2372974242C134018914 @default.
- W2372974242 hasConceptScore W2372974242C16685009 @default.
- W2372974242 hasConceptScore W2372974242C185592680 @default.
- W2372974242 hasConceptScore W2372974242C190283241 @default.
- W2372974242 hasConceptScore W2372974242C2778206080 @default.
- W2372974242 hasConceptScore W2372974242C2780091579 @default.
- W2372974242 hasConceptScore W2372974242C2780159080 @default.
- W2372974242 hasConceptScore W2372974242C2780931953 @default.
- W2372974242 hasConceptScore W2372974242C31573885 @default.
- W2372974242 hasConceptScore W2372974242C55493867 @default.
- W2372974242 hasConceptScore W2372974242C71924100 @default.
- W2372974242 hasConceptScore W2372974242C86803240 @default.
- W2372974242 hasIssue "1" @default.
- W2372974242 hasLocation W23729742421 @default.
- W2372974242 hasOpenAccess W2372974242 @default.
- W2372974242 hasPrimaryLocation W23729742421 @default.
- W2372974242 hasRelatedWork W2039391269 @default.
- W2372974242 hasRelatedWork W2136460167 @default.
- W2372974242 hasRelatedWork W2322362843 @default.
- W2372974242 hasRelatedWork W2350788618 @default.
- W2372974242 hasRelatedWork W2352451238 @default.
- W2372974242 hasRelatedWork W2357335842 @default.
- W2372974242 hasRelatedWork W2360599521 @default.
- W2372974242 hasRelatedWork W2364742006 @default.
- W2372974242 hasRelatedWork W2367382116 @default.
- W2372974242 hasRelatedWork W2369751745 @default.
- W2372974242 hasRelatedWork W2370556798 @default.
- W2372974242 hasRelatedWork W2378074379 @default.
- W2372974242 hasRelatedWork W2380412611 @default.
- W2372974242 hasRelatedWork W2380426620 @default.
- W2372974242 hasRelatedWork W2389476759 @default.
- W2372974242 hasRelatedWork W2390510709 @default.
- W2372974242 hasRelatedWork W2409478626 @default.
- W2372974242 hasRelatedWork W2466974137 @default.
- W2372974242 hasRelatedWork W814813869 @default.
- W2372974242 hasRelatedWork W2466972576 @default.
- W2372974242 hasVolume "27" @default.
- W2372974242 isParatext "false" @default.
- W2372974242 isRetracted "false" @default.
- W2372974242 magId "2372974242" @default.
- W2372974242 workType "article" @default.