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- W2373053099 abstract "Objective To determine the protective effect of magnesium fortified drinking water on experimental atherosclerosis formation in rats. Methods Levels of blood lipids,TNF-α and IL-6 in serum and homogenized tissue were determined. Pathological changes of the aorta were evaluated in control group ( fed with normal diet and water) , model group ( fed with high-fat diet and normal water) and study group (fed with high-fat diet and magnesium fortified water) at the end of 8 weeks. Results 1 ) TNF-α and IL-6 in the myocardium and aorta were significantly higher in model group than those in study group and control group(P0.05) ;serum TNF-α was not detected; serum IL-6 in model group was significantly higher than that in the other 2 groups ( P 0.01) ; 2) Lipid file analysis showed that TC, TG and LDL-C in model group and study group were higher than those in control group ( P 0. 05 ) , and they were significantly lower in study group than those in model group ( P 0. 05) ; HDL-C/TC in study group was higher than that in model group ( P 0.05); 3) The score of atherosclerotic plaque evaluation was significantly lower in study group than that in model group ( P 0. 05). Conclusion Fortified magnesium has a preventive effect on atherosclerosis formation, probably through down-regulation of inflammatory factors." @default.
- W2373053099 created "2016-06-24" @default.
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- W2373053099 date "2005-01-01" @default.
- W2373053099 modified "2023-09-26" @default.
- W2373053099 title "Preventive Effect of Magnesium Fortified Drinking Water on Experimental Atherosclerosis Formation in Rats" @default.
- W2373053099 hasPublicationYear "2005" @default.
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