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- W2373071708 abstract "Objective The present study is to investigate the expression of aB-crystallin in normal lens of rat of different ages,and to explore the relationships between the expression of αB-crystallin and age-related cataract.Methods Lenses were obtained from general Wistar rats of 3,6,9,12weeks old(10 lenses) and homogenized with different concentrations of standard bovine serum.The proteins were resolved using SDS-PAGE gel electrophoresis,Total concentration of aB-crystallin in lenses from rats of different ages were detected by the way of Western blot.Results aB-crystallin was detected at a molecular weight of 23.5 kDa.The total concentration of aB-crystallin in rat lenses decreased with the growth of age.Conclusion aB-crystallin may be involved in the alteration of crystallin during the development of lenses,and it may play an important role in the formation and aggravation of age-related cataract." @default.
- W2373071708 created "2016-06-24" @default.
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- W2373071708 date "2012-01-01" @default.
- W2373071708 modified "2023-09-24" @default.
- W2373071708 title "The expression of αB-orgstallin in normal lens of rat of different ages" @default.
- W2373071708 hasPublicationYear "2012" @default.
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