Matches in SemOpenAlex for { <https://semopenalex.org/work/W2373166626> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2373166626 abstract "Objectives To investigate the expression of bcl-2,vascular endothelial growth factor(VEGF) in breast cancer, and the relationship of these two factors. Method Sixty-four women of primary breast carcinoma were studied for the expression of bcl-2 and VEGF proteins with the method of automated immunohistochemical assay.Results Forty-two(66%) and forty(62%)breast cancer cases were found positive for bcl-2 and VEGF.A statistically significant association was found between the bcl-2 expression and the high grading,positive lymph nodes,estrogen receptor(ER) positivity,progestin receptor(PR) positivity.Bcl-2 may extend the viability of cells containing genetic alterations,and facilitate tumor progression.The VEGF expression is negatively related to the ER and PR;VEGF is positivily related to tumor size,lymph nodes,high grading;besides bcl-2 and VEGF themselves also have a positive correlation. Conclutions ①Disorder of bcl-2 expression made the breast cancer cells have a disorder in apoptosis′ modulation,so promoting the cancer cell′s growth and axillary lymphnode metastasis,even affecting their biological behavior;②VEGF,via its enhancing the cancer cells′ microvascularization and raising their permeability,takes part in the cancer′s invasion and metastasis;③The interaction of VEGF and bcl-2 participates in the genesis and development of breast cancer;④Researching the VEGF and bcl-2 expression offered a theoretical basis for the gene-targeted therapy and antivascularization." @default.
- W2373166626 created "2016-06-24" @default.
- W2373166626 creator A5043195371 @default.
- W2373166626 date "2005-01-01" @default.
- W2373166626 modified "2023-09-26" @default.
- W2373166626 title "Prognostic value of bcl-2 and vascular endothelial growth factor in breast cancer" @default.
- W2373166626 hasPublicationYear "2005" @default.
- W2373166626 type Work @default.
- W2373166626 sameAs 2373166626 @default.
- W2373166626 citedByCount "0" @default.
- W2373166626 crossrefType "journal-article" @default.
- W2373166626 hasAuthorship W2373166626A5043195371 @default.
- W2373166626 hasConcept C121608353 @default.
- W2373166626 hasConcept C126322002 @default.
- W2373166626 hasConcept C142724271 @default.
- W2373166626 hasConcept C143998085 @default.
- W2373166626 hasConcept C167734588 @default.
- W2373166626 hasConcept C18903297 @default.
- W2373166626 hasConcept C204232928 @default.
- W2373166626 hasConcept C2777025900 @default.
- W2373166626 hasConcept C2777286243 @default.
- W2373166626 hasConcept C2779013556 @default.
- W2373166626 hasConcept C3018521938 @default.
- W2373166626 hasConcept C502942594 @default.
- W2373166626 hasConcept C530470458 @default.
- W2373166626 hasConcept C71924100 @default.
- W2373166626 hasConcept C84606932 @default.
- W2373166626 hasConcept C86803240 @default.
- W2373166626 hasConceptScore W2373166626C121608353 @default.
- W2373166626 hasConceptScore W2373166626C126322002 @default.
- W2373166626 hasConceptScore W2373166626C142724271 @default.
- W2373166626 hasConceptScore W2373166626C143998085 @default.
- W2373166626 hasConceptScore W2373166626C167734588 @default.
- W2373166626 hasConceptScore W2373166626C18903297 @default.
- W2373166626 hasConceptScore W2373166626C204232928 @default.
- W2373166626 hasConceptScore W2373166626C2777025900 @default.
- W2373166626 hasConceptScore W2373166626C2777286243 @default.
- W2373166626 hasConceptScore W2373166626C2779013556 @default.
- W2373166626 hasConceptScore W2373166626C3018521938 @default.
- W2373166626 hasConceptScore W2373166626C502942594 @default.
- W2373166626 hasConceptScore W2373166626C530470458 @default.
- W2373166626 hasConceptScore W2373166626C71924100 @default.
- W2373166626 hasConceptScore W2373166626C84606932 @default.
- W2373166626 hasConceptScore W2373166626C86803240 @default.
- W2373166626 hasLocation W23731666261 @default.
- W2373166626 hasOpenAccess W2373166626 @default.
- W2373166626 hasPrimaryLocation W23731666261 @default.
- W2373166626 hasRelatedWork W2348470290 @default.
- W2373166626 hasRelatedWork W2350383194 @default.
- W2373166626 hasRelatedWork W2350703824 @default.
- W2373166626 hasRelatedWork W2357241361 @default.
- W2373166626 hasRelatedWork W2367757060 @default.
- W2373166626 hasRelatedWork W2368772557 @default.
- W2373166626 hasRelatedWork W2370574415 @default.
- W2373166626 hasRelatedWork W2370631071 @default.
- W2373166626 hasRelatedWork W2371880365 @default.
- W2373166626 hasRelatedWork W2375178356 @default.
- W2373166626 hasRelatedWork W2376479618 @default.
- W2373166626 hasRelatedWork W2382496294 @default.
- W2373166626 hasRelatedWork W2383454234 @default.
- W2373166626 hasRelatedWork W2384397516 @default.
- W2373166626 hasRelatedWork W2388234549 @default.
- W2373166626 hasRelatedWork W2391570238 @default.
- W2373166626 hasRelatedWork W2394304793 @default.
- W2373166626 hasRelatedWork W2474243817 @default.
- W2373166626 hasRelatedWork W2475118044 @default.
- W2373166626 hasRelatedWork W3142650349 @default.
- W2373166626 isParatext "false" @default.
- W2373166626 isRetracted "false" @default.
- W2373166626 magId "2373166626" @default.
- W2373166626 workType "article" @default.