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- W2373195888 abstract "Objective To investigate the value of contrast-enhanced ultrasonography(CEUS) in differential diagnosis of focal liver lesions(FLL).Methods Thirty-nine patients with 52 focal liver lesions,including 28 benign and 24 malignant,were examined with pulse-inversion harmonic imaging(PIHI) after injection of contrast agent(SonoVue).The CEUS features were studied,including predominant enhancement phases,arrival time of contrast agent,enhancement peak time,enhancement patterns,and time-intensity curve(TIC).The diagnostic consistency rate of differentiation between benign and malignant FLL was calculated respectively.Results In respect of predominant enhancement phases,the high enhancement on CEUS was shown in 75%(21/28) of benign FLL and in 92.6%(22/24) of malignant FLL in arterial phase(P=0.113).In portal and delayed phases,the high enhancement was seen more often in benign FLL(75%,21/28;60.7%,17/28),while the low or no enhancement was visualized more often in malignant FLL(91.6%,22/24;100%,24/24)(P=0.000).The diagnostic consistency rate of differentiation between benign and malignant FLL was 92.3%.The arrival time of contrast agent of benign and malignant FLL was(21.52±6.70)s and(17.82±6.04)s(P=0.058).The enhancement peak time of benign and malignant FLL was(46.26±14.97)s and(27.32±8.55)s(P=0.000).The diagnostic consistency rate of differentiation between benign and malignant FLL was 78.6%.The stastistical significance was found in benign and malignant FLL of pattern I,pattern III,pattern IV and pattern VI(P=0.029,P=0.000,P=0.036,P=0.029).The diagnostic consistency rate of differentiation between benign and malignant FLL was 84.1%.TIC of benign FLL was predominantly depicted as a type of fast-up and slow-down curve(82.6%),while that of the malignant was mostly described as a type of fast-up and fast-down curve(90.9%)(P=0.000).The diagnostic consistency rate of differentiation between benign and malignant FLL was 95.1%.Conclusion There are some helpful CEUS parameters that are predominant enhancement phases,TIC,enhancement peak time and enhancement patterns;in particular,predominant enhancement phases and TIC have a diagnostic consistency rate of more than 90% in the differentiation of benign and malignant FLL.CEUS is useful for the differential diagnosis of benign and malignant FLL." @default.
- W2373195888 created "2016-06-24" @default.
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- W2373195888 date "2008-01-01" @default.
- W2373195888 modified "2023-09-23" @default.
- W2373195888 title "The application of contrast-enhanced ultrasonography in differential diagnosis of focal liver lesions" @default.
- W2373195888 hasPublicationYear "2008" @default.
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