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- W2373203487 abstract "Objective:To study the changes of cytokines in patients with multiple trauma and its clinical significance.Methods:The concentration of nitric oxide (NO) was detected by colorimetry,the TNF-2 was determined by radioimmunoassay and IL-4 was measured by enzyme linked immunosorbent assay(ELISA)in 62 patients with multiple trauma at admission and 12 hours,1,2,3,7 and 14 days,and were compared with those in the healthy control group simultaneously.Results:The serum NO、TNF-α and IL-4 in patients with multiple trauma were shown to be significantly higher than those in the control group.The nitric oxide,TNF-αand 1L-4 increased at the early stage and reached the peak at 3 days and subsequently decreased gradually in 2 weeks after trauma.The ISS scores of patients were positively correlated with the peaks of nitric oxide,TNF-α and IL-4.Conclusion:Investigating the changes of cytokines in patients with multiple trauma would contribute to evaluate the patient's condition and judge the prognosis of this disease." @default.
- W2373203487 created "2016-06-24" @default.
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- W2373203487 date "2006-01-01" @default.
- W2373203487 modified "2023-09-23" @default.
- W2373203487 title "Changes of cytokine index in patients with multiple trauma and its clinical significance" @default.
- W2373203487 hasPublicationYear "2006" @default.
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