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- W2373252372 abstract "Purpose To identify the regulation of change of acidic fibroblast growth factor receptor in rat gut ischemia-reperfusion (I/R) injury after the administration of acidic fibroblast growth factor (aFGF). Methods Rat I-R injury was produced by clamping the superior mesenteric artery (SMA), and the animals were divided randomly into sham operation group(C), normal saline control group(R), reconstructive human aFGF treatment group(F). Blood samples and tissue specimens were collected at 2, 6, 12,and 24 hours after reperfusion. The expression of FGFR and the levels of FGFR mRNA were detected. Results The expression of FGFR mRNA increased gradually after I/R injury and peaked at 6 hours after reperfusion. The expression level in group F was higher than that in group R.Conclusion The protective effect of aFGF on the intestine after I/R injury might be mediated by the activation of FGF receptor." @default.
- W2373252372 created "2016-06-24" @default.
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- W2373252372 date "2007-01-01" @default.
- W2373252372 modified "2023-09-23" @default.
- W2373252372 title "Expression of acidic fibroblast growth factor in rat gut ischemia/reperfusion injury" @default.
- W2373252372 hasPublicationYear "2007" @default.
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