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- W2373345280 abstract "Objective:To discuss and evaluate the method of establishing the model of synovitis on rabbit′s knee joint. Method:48 rabbits were devided into 4 groups at random, each group had 12. Rabbits were anaesthetised with 3% sodium pentobarbital. The rabbit′s hindlimbs were sticked vertically at the midpoint of quadriceps femoris and gastrocnemius muscles, connecting electroacupuncture apparatus, 50Hz with a frequency, 1.5mA intensity. Causing their knee joints did passive flexion and extension without intermission, twice a day,ten days. Measuring the change of rabbit′s knee joint circumference, the time of limp after being stimulated, the change of joint surface′s temperature etc. Estimating the inflammation of knee joint locally with the test of ECT,injecting 1ml Saline into the knee joint cavity,draw out the joint fluid to test the level of inflammation factors such as IL-1β,PGE2,SOD,MDA. Synovium was removed for pathological section,immunohistochemistry etc. Result:Every detecting markers of model limbs were notable significance compared with the normal limbs(P0.05,P0.01),the pathological section of synovium showed inflammational bleeding. Moreover,the longer the time of sticking, the more significant. Conclusion:The model of synovitis of rabbit's knee is successful. The method is feasible, economical applicable, and worth popularizing." @default.
- W2373345280 created "2016-06-24" @default.
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- W2373345280 date "2005-01-01" @default.
- W2373345280 modified "2023-09-24" @default.
- W2373345280 title "The establishment and estimation on the model of traumatic synovitis in rabbit's knee" @default.
- W2373345280 hasPublicationYear "2005" @default.
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