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- W2373365544 abstract "Objective:To investigate the effects of short-term insulin glargine on plasma glucose,and the change of beta-cell function and insulin resistance in Primary type 2 diabetes mellitus(T2DM) patients.Method :36 newly diagnosed T2DM cases complicated with fasting plasma glucose(FPG)≥11.1 mmol/L,were treated with glargine insulin around 22:00 each day and regular human insulin before lunch and dinner each day.After two weeks the patients were followed by the withdrawal of medicine.Result:The excellent control of plasma glucose was achieved after 2 weeks treatment with glargine insulin.Beta-cell function was dramatically improved.The secretion index of insulin and C-peptide curve area as well as Homa-β were sign were obviously increased during OGTT.Re-examined patients stopped using of medicine for at most four months,whose plasma glucose could be controlled only by controlling of diet and exercise.Conclusion:The excellent glucose control,improvement of beta-cell function,and amelioration of insulin resistance can be induced by short-term glargine treatment in Primary type 2 diabetic patients." @default.
- W2373365544 created "2016-06-24" @default.
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- W2373365544 date "2009-01-01" @default.
- W2373365544 modified "2023-09-26" @default.
- W2373365544 title "The Effect of β-cell Function on Insulin Glargine in the Treatment of Primary Type 2 Diabetes Mellitus" @default.
- W2373365544 hasPublicationYear "2009" @default.
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