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- W2373445982 abstract "Objective To study the expression and diagnostic value of p27 and CD44V6 in ovarian carcinomas.Methods 54 cases of ovarian carcinoma were examined by immunohistochemical two-step-system method for p27 and CD44V6.Results The positive rates of p27 and CD44V6 is 37.0 %(20/54),42.6 %(23/54) respectively.The positive rates of p27 is 20.0 %,12.0 % and 8.7 % in clinic stage Ⅲ~Ⅳ,poorly differentiated tumors and lymphnode metastasis group compared with 68.4 %,58.6 % and 58.1 % in clinic stageⅠ~Ⅱ,well differentiated tumors and lymphnode negative group(P 0.05,P 0.05 and P 0.01).The positive rate of CD44V6 is 57.1 %,73.9 % in clinic stage Ⅲ~Ⅳ and lymphnode metastasis group compared with 15.8 %,19.4 % in clinic stageⅠ~Ⅱ and lymphnode negative group(P 0.05,P 0.05.Conclusions The negative expression of p27 and the over expression of CD44V6 may play an important role in the development of ovarian carcinomas.Both of them were important in predicting the biological behavior and prognosis of ovarian carcinomas." @default.
- W2373445982 created "2016-06-24" @default.
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- W2373445982 date "2006-01-01" @default.
- W2373445982 modified "2023-09-23" @default.
- W2373445982 title "Expression and diagnostic value of p27 and CDV in ovarian carcinomas" @default.
- W2373445982 hasPublicationYear "2006" @default.
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