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- W2373484967 abstract "Contacts between the serotonergic fibers and the parvalbumin (PV) expressing second order neurons on the four order central pathway of the trigeminal proprioception of the rat have been observed by using triple labeling of immunofluorescence histochemistry under the confocal laser scanning microscope. The results showed that after the injection of tetramethylrhodamine dextran amine (TMR DA) into the dorsomedial part of the principal sensory trigeminal nucleus (Vpdm) and the triple immunofluorescence for PV, serotonin (5 HT) and TMR DA, plexus of fibers with 5 HT like immunoreactivity (5 HT LI) and many neurons double labeled with PV/TMR DA were detected in the dorsomedial part of the subnucleus oralis of the spinal trigeminal nucleus and its adjacent lateral reticular formation (Vodm LRF). Some en passant or terminal boutons with 5 HT LI were detected to be in close apposition to the dendrites or cell bodies of the PV /TMR DA double labeled neurons. The results suggested that the serotonergic fibers may synapse upon the PV expressing second order neurons and 5 HT may have modulatory effects on the trigeminal proprioceptive information at the level of second order neurons on the four order central pathway of the trigeminal proprioception of the rat. [" @default.
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- W2373484967 date "2001-01-01" @default.
- W2373484967 modified "2023-09-25" @default.
- W2373484967 title "Serotonergic fibers in close apposition to the parvalbumin-expressing second-order neurons on the four-order central pathway of the trigeminal proprioception in the rat" @default.
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