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- W2373502138 abstract "Epidemiology investigations demonstrate significantly negative correlation between the parasitic infection and the incidence of inflammatory bowel disease(IBD) which includes ulcerative colitis(UC) and Crohn's disease(CD).Both animal and clinical studies are employed to explore the mechanism.After parasites especially helminthic infected,the host of gastrointestinal tract mainly appears the Th2 immune response.Immunocytes are activated and cytokines are secreted,resulting in elimination of the invaded parasites as well as recovery of intestinal injury.Then,the host after the repair of intestinal lesions will be resistant to the onset or relapse of IBD.Intestinal damage would be ameliorated after artificial infection with helminth ova in IBD.These studies are helpful to elucidate the mechanism of intestinal damages and develop novel therapeutic strategies." @default.
- W2373502138 created "2016-06-24" @default.
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- W2373502138 date "2009-01-01" @default.
- W2373502138 modified "2023-09-26" @default.
- W2373502138 title "The negative correlation study of parasitic infection and inflammatory bowel disease" @default.
- W2373502138 hasPublicationYear "2009" @default.
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