Matches in SemOpenAlex for { <https://semopenalex.org/work/W2373513672> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2373513672 abstract "Objective To study the effects of hypoxia ischemia (HI) on long term learning and memory abilities and hippocampal pyramidal neurons and the efficacy of nimotop in treating hypoxic ischemic brain damage. Methods 34 seven day old postnatal Wistar rats were subjected to right common carotid artery ligation followed by exposure to 8% oxygen at 37℃ for 2hr. The animals were divided into two groups randomly. 13 rat pups received an intraperitoneal injection of 160μg/kg body weight nimotop per day immediately following cerebral hypoxia ischemia for five days. Control animals received an equivalent volume of normal saline (n=21). When the rats were 80 to 90 day old, they were gave test of Y maze discrimination learning and memory keeping percentage and the brain tissues were for neuropathological examination. Results Hypoxia ischemia significantly decreased Y maze discrimination learning and memory abilities (P0.01,P0.05) and the numerical density of hippocampal CA1 pyramidal cells (P 0.01 ).Nimotop significantly increased Y maze discrimination learning (P0.01) of rats after HI and had no effect on memory keeping. In this group nimotop increased the numerical density of hippocampal CA1 pyramidal neurons (P0.01). Conclusion Nimotop might be effective to rescue hippocampal CA1 pyramidal neurons damaged by HI and improve the ability of Y maze discrimination learning, but had no effect on memory keeping." @default.
- W2373513672 created "2016-06-24" @default.
- W2373513672 creator A5050182302 @default.
- W2373513672 date "2001-01-01" @default.
- W2373513672 modified "2023-09-25" @default.
- W2373513672 title "The effects of nimotop on long-term learning and memory of perinatal rats after hypoxia-ischemia" @default.
- W2373513672 hasPublicationYear "2001" @default.
- W2373513672 type Work @default.
- W2373513672 sameAs 2373513672 @default.
- W2373513672 citedByCount "0" @default.
- W2373513672 crossrefType "journal-article" @default.
- W2373513672 hasAuthorship W2373513672A5050182302 @default.
- W2373513672 hasConcept C109344038 @default.
- W2373513672 hasConcept C126322002 @default.
- W2373513672 hasConcept C134018914 @default.
- W2373513672 hasConcept C148762608 @default.
- W2373513672 hasConcept C15744967 @default.
- W2373513672 hasConcept C178790620 @default.
- W2373513672 hasConcept C185592680 @default.
- W2373513672 hasConcept C2777397205 @default.
- W2373513672 hasConcept C2780159080 @default.
- W2373513672 hasConcept C2781064879 @default.
- W2373513672 hasConcept C2987047532 @default.
- W2373513672 hasConcept C42219234 @default.
- W2373513672 hasConcept C540031477 @default.
- W2373513672 hasConcept C541997718 @default.
- W2373513672 hasConcept C71924100 @default.
- W2373513672 hasConcept C7836513 @default.
- W2373513672 hasConceptScore W2373513672C109344038 @default.
- W2373513672 hasConceptScore W2373513672C126322002 @default.
- W2373513672 hasConceptScore W2373513672C134018914 @default.
- W2373513672 hasConceptScore W2373513672C148762608 @default.
- W2373513672 hasConceptScore W2373513672C15744967 @default.
- W2373513672 hasConceptScore W2373513672C178790620 @default.
- W2373513672 hasConceptScore W2373513672C185592680 @default.
- W2373513672 hasConceptScore W2373513672C2777397205 @default.
- W2373513672 hasConceptScore W2373513672C2780159080 @default.
- W2373513672 hasConceptScore W2373513672C2781064879 @default.
- W2373513672 hasConceptScore W2373513672C2987047532 @default.
- W2373513672 hasConceptScore W2373513672C42219234 @default.
- W2373513672 hasConceptScore W2373513672C540031477 @default.
- W2373513672 hasConceptScore W2373513672C541997718 @default.
- W2373513672 hasConceptScore W2373513672C71924100 @default.
- W2373513672 hasConceptScore W2373513672C7836513 @default.
- W2373513672 hasLocation W23735136721 @default.
- W2373513672 hasOpenAccess W2373513672 @default.
- W2373513672 hasPrimaryLocation W23735136721 @default.
- W2373513672 hasRelatedWork W1969031947 @default.
- W2373513672 hasRelatedWork W1980107137 @default.
- W2373513672 hasRelatedWork W2048015206 @default.
- W2373513672 hasRelatedWork W2076507975 @default.
- W2373513672 hasRelatedWork W2257301736 @default.
- W2373513672 hasRelatedWork W2354096456 @default.
- W2373513672 hasRelatedWork W2359025846 @default.
- W2373513672 hasRelatedWork W2359586041 @default.
- W2373513672 hasRelatedWork W2359796463 @default.
- W2373513672 hasRelatedWork W2365545561 @default.
- W2373513672 hasRelatedWork W2366867968 @default.
- W2373513672 hasRelatedWork W2373178111 @default.
- W2373513672 hasRelatedWork W2382580278 @default.
- W2373513672 hasRelatedWork W2384615581 @default.
- W2373513672 hasRelatedWork W2390265314 @default.
- W2373513672 hasRelatedWork W2393324037 @default.
- W2373513672 hasRelatedWork W3024808408 @default.
- W2373513672 hasRelatedWork W3029578784 @default.
- W2373513672 hasRelatedWork W3031278337 @default.
- W2373513672 hasRelatedWork W346030584 @default.
- W2373513672 isParatext "false" @default.
- W2373513672 isRetracted "false" @default.
- W2373513672 magId "2373513672" @default.
- W2373513672 workType "article" @default.