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- W2373534231 abstract "Objective To observe the effects of angiotensin Ⅱ(Ang Ⅱ) on intracellular calcium concentration ([Ca 2+] i) in guinea pig isolated ventricular myocytes under simulated ischemia condition.Method Using Fluo-3/AM loading and confocal microscopy, the effects of Ang Ⅱon [Ca 2+] i were observed in guinea pig isolated ventricular myocytes under simulated ischemia condition, which mimicked hypoxia,glucose deficient,high lactic acid and acidosis.Result [Ca 2+] i increased steadily during the period of simulated ischemia, while Ang II resulted in a periodic pulse-like increase in [Ca 2+] i.Conclusion Ang Ⅱ may increase [Ca 2+] i during the period of simulated ischemia which result in calcium overload." @default.
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- W2373534231 date "2003-01-01" @default.
- W2373534231 modified "2023-10-17" @default.
- W2373534231 title "Effect of angiotensin II on intracellular calcium concentration of ischemic ventricular myocytes of the guinea pig" @default.
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