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- W2373565836 abstract "Objective To establish a new animal model of arrhythmia on Sprague-Dawley rats.Methods To give aconite fat-soluble alkaloids 0.425 mg.kg~(-1) in the femoral vein rapidly and record the ECG with four-channel polygraph.Results Aconite fat-soluble alkaloids can induce premature ventricular contraction,bigeminy or trigeminy,short-term paroxysmal ventricular tachycardia,continuous ventricular tachycardia,followed by a gradual in reverse order recovery.Treatment with lidocaine was significantly different than normal saline(P 0.001).Conclusion The establishment of an arrhythmia animal model in rats using aconite fat-soluble alkaloids is a feasible approach." @default.
- W2373565836 created "2016-06-24" @default.
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- W2373565836 date "2010-01-01" @default.
- W2373565836 modified "2023-09-23" @default.
- W2373565836 title "Establishment of an Aconite Fat-soluble Alkaloids Arrhythmia Model in Rats" @default.
- W2373565836 hasPublicationYear "2010" @default.
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